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The pro-cognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-Met system

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The CD38generated cADPR, in turn, augments the IFNs-induced ISGs and NF-B-mediated inflammation, leading to the antiviral hyperinflammation response

doi: 10.3389/fnagi.2025.1719179 Received 05 October 2025 Revised 20 November 2025 Accepted 25 November 2025 Published 15 December 2025 Corrected 23 February 2026 Volume 17 - 2025 Edited by Thomas Van Groen, University of Alabama at Birmingham, United States Reviewed by Jos Manuel Reales, National University of Distance Education (UNED), Spain Hamza Kk, Ondokuz Mays University, Trkiye Updates Copyright 2025 Liang, Liu, Yan, Xu, Dai and Huang

it is an unapproved research chemical , not a medicine, with no human efficacy, safety, or pharmacokinetic data presented for research and educational use only